How to read (transcription):
[nye v see-BYE]
(lit. – out of oneself)
1. crazy, wacko, nuts, not in his right mind
2. in a bad state, thrown off balance
Leave him, he is not in his right mind.
More from "Conversational Russian"
the one who follows pofigism
to have one's plans ruined, not to get anything desired
from "бок", side of the car
greenhorn, snotnose, milksop, wimp, spineless creature
to drink alcohol
~ to send to hell (check out this episode for more details)